ZBiotics — Feel Better After Drinking, Wake Up Refreshed, Science-Backed, Patented Probiotic for Easier Mornings, Travel-Friendly, 6-Pack of 0.5 Fl Oz Bottles

ZBiotics Pre-Alcohol (or Pre-Alcohol for short) is a beverage containing a patented, genetically engineered probiotic (B. subtilis ZB183™) that helps you land on your feet the day after drinking alcohol. It’s engineered to break down an unwanted byproduct of alcohol called acetaldehyde – the main culprit behind rough mornings after drinking.*

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Pre-Alcohol is designed to replicate the natural process of your liver, but do it in your gut. We took a normal probiotic bacteria you already eat every day, and we bioengineered it to produce the same type of enzyme your liver produces. That enzyme breaks down acetaldehyde – an unwanted byproduct of alcohol that accumulates in your gut when you drink.

Your liver does not have access to your gut. But by drinking Pre-Alcohol, the goal is to augment your gut’s natural ability to digest acetaldehyde while you drink and while you sleep – helping you make the most of the next day. Just remember that Pre-Alcohol won’t affect intoxication or make alcohol safer to drink, so always drink responsibly.

The earlier the better. Ideally you drink Pre-Alcohol before your first drink.

The probiotic in Pre-Alcohol needs time to “wake up” in your gut, so we say the earlier the better if you can remember it. We drink Pre-Alcohol just before going out – right before our first drink. But it should be active if you drink it any time during the day or night. So whether it’s a few hours before drinking or you’ve already enjoyed a round or two, go for it. Pre-Alcohol can help from that point on.

The probiotic in Pre-Alcohol is likely to stay in your body for 18-24 hours after you drink it. So one bottle will cover you for a whole day, even if you're starting with brunch mimosas followed by evening plans later on!

1. Drink 1 bottle of Pre-Alcohol.
2. Enjoy your night.
3. Get some sleep.

Drink Pre-Alcohol before or during drinking – the earlier the better. Just give it a shake and drink the whole thing. The probiotics are designed to become active while you drink and while you sleep, helping your body digest acetaldehyde as they’re passing through your gut. Then they simply leave your body after a day or two, without changing your body or impacting your microbiome. A happier, healthier you, thanks to ZBiotics Pre-Alcohol.

It's the good stuff.

It's just the natural sedimentation of the probiotic and the flavoring that happens if the bottle is left resting for a while. Just give it a couple shakes to re-suspend and you're good to go.

The flavor is a bit tart with minimal aftertaste (like lemon water). 

The texture is just like water. The probiotic should make the liquid slightly cloudy unless it settles in the bottle. So give it a shake and watch all the ingredients mix together before drinking.

Acetaldehyde (pronounced “asset” + “AL” + “duh” + “hide”) is a chemical we most often experience as a byproduct of alcohol metabolism. It’s linked to lots of unwanted effects on our bodies, but most commonly it’s associated with the rough feelings you get the day after drinking.

When we drink, our bodies break down alcohol in 2 steps. 

1. From ethanol to acetaldehyde. 
2. From acetaldehyde to acetate (essentially vinegar). 

The first reaction (ethanol to acetaldehyde) moves quickly, but the second reaction (acetaldehyde to acetate) is less efficient, particularly in the gut. That’s because your gut has drastically lower amounts of the acetaldehyde-digesting enzyme. So when we drink, acetaldehyde tends to build up in the gut, which is bad news, because normal responsible drinking habits like hydrating and eating are unlikely to increase your body’s ability to digest acetaldehyde. So you’re probably going to feel it. Good news, ZBiotics Pre-Alcohol is here to help.

Room temperature. No refrigeration needed.

Store Pre-Alcohol at room temperature with the cap on. Do not refrigerate. Try not to open it until you’re ready to drink it; opening it could potentially let contaminants from the air into the bottle.

It probably won't do anything.

Pre-Alcohol won’t do much if consumed substantially after a round of drinking. Pre-Alcohol’s key ingredient – the probiotic that breaks down acetaldehyde – needs time to “wake up” in your gut and become active. That’s why we make Pre-Alcohol our first drink of the night.

Pre-Alcohol expires 18 months after bottling. We aim to deliver products to you that still have at least 12 months of shelf-life left. Check the “BB” (Best-By) date on your bottle or box.

Store Pre-Alcohol at room temperature with the cap on. Do not refrigerate. Do not open it until you’re ready to drink it; opening it could potentially let contaminants from the air into the bottle.

One rarely appreciated fact is that your gut, and particularly your colon (part of your gut), is actually a huge sink and source of acetaldehyde in the body, even more so than the blood or liver. In fact, acetaldehyde concentrations in the colon are 10 to 100 times higher than in the blood. That’s because a large amount of acetaldehyde is actually created in your gut, produced by enzymes in both your intestinal lining and your microbiome.

But acetaldehyde doesn’t just stick around your gut. It’s an extremely soluble molecule. So soluble, in fact, that it can actually diffuse into all the fluid of your body, easily passing through membranes from your gut and into your brain, muscles, and cells. The result? All those non-gut effects of acetaldehyde may in fact be quite gut-related.

Other products on the market today are different mixes of the same ~10 off-the-shelf vitamins and plant extracts you can find anywhere. Many of these have absolutely no demonstration of efficacy or even really a hypothesis as to how they could possibly help you.

Pre-Alcohol is different. We looked at one of the major unwanted byproducts of drinking alcohol – acetaldehyde – and invented a probiotic bacteria to break it down the same way your liver does. 

No other product out there does that.